Diagnostic Antibodies

All of the diagnostic antibodies listed have been evaluated with clinical samples.

Rabbit monoclonal antibody clones for procalcitonin (PCT)

AvantGen has generated a compatible pair of high affinity rabbit monoclonal diagnostic antibodies against human PCT. Thus, these clones are suitable for high sensitivity PCT assay development.

Rabbit monoclonal antibodies for NT-proBNP

AvantGen has generated a compatible pair of rabbit monoclonal diagnostic antibodies against the NT-proBNP. They display higher affinities than other commercially available antibody clones, with a corresponding increase in assay sensitivity. Thus, these clones are suitable for high sensitivity NT-proBNP assay development.

Rabbit monoclonal antibodies for Strep-A

AvantGen has developed rabbit monoclonal diagnostic antibodies that recognizes with high affinity all Strep A strains tested to date. These antibodies do not recognize Strep B, C, F or G. Thus, these antibodies are suitable for diagnostic kit development. These antibodies have been shown to outperform rabbit polyclonal antibodies in the similar assays.

Rabbit and human monoclonal antibody clones for GPBB

AvantGen’s anti-GPBB antibody clones are highly specific and show no cross-reactivity to GPLL and GPMM. Thus, these are suitable for sensitive GPBB assay development.

Human monoclonal antibodies for PAPP-A

AvantGen has developed compatible high affinity human monoclonal diagnostic antibodies that specifically identify the PAPP-A subunit relevant to cardiovascular disease for diagnostic purposes. They show no cross-reactivity to either proEBP or related metalloproteinases such as PAPP-A2 or MMP-9. Thus, these clones are suitable for high sensitivity PAPP-A assay development.

Heart-type Fatty Acid Binding Proteins (H-FABP)

AvantGen has generated a compatible pair of high affinity rabbit monoclonal diagnostic antibodies against human H-FABP. Thus, these clones are suitable for high sensitivity H-FABP assay development.

Rabbit monoclonal antibodies for Glucagon

AvantGen has generated a compatible pair of high affinity rabbit monoclonal diagnostic antibodies against human Glucagon. These antibodies will only detect the mature, cleaved form of glucagon and not the precursor proglucagon.  Furthermore, they will not cross-react to the related mini-glucagon, oxyntomodulin, and glicentin proteins. Thus, these clones are suitable for high sensitivity Glucagon assay development.