AvantGen’s human antibody libraries can be rapidly screened by magnetic bead based sorting (MACS) and fluorescence-activated cell sorting (FACS) for antibody clones with the desired characteristics, including:
- Specificity for isoform or conformation/epitope of interest
- Species-cross reactivity, such as recognizing human, Cyno, Rhesus and mouse antigen
- Blocking activity
The above features can be designed and incorporated into library screening resulting in generating full-length human IgG antibody clones with the desired characteristics in 8-10 weeks.